How to fix This application cannot run on the PC under Windows 10? You may have received this message on your computer screen if you tried to run software that has just been installed, an application after a long period of time, or a program after installing updates. Well, if you have this question, this post suggests some settings you need to look at and shows you how to solve the problem.
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Several users received this message when installing iTunes, Lotus SmartSuite, Simple Assembly Explorer, AutoDesk, Daemon Tools, etc. But this message can appear for any application.
When you see this message, you must first check if the software has updates. Visit the software manufacturer’s website and make sure you are using the latest version of the application. If you notice that a new version has been released, download and install the new version. That should help. If not, there may be other things you need to do.
1] Check whether the program is intended for your Windows version – 32 bits or 64 bits. You may be using 32-bit Windows and unknowingly trying to run a 64-bit program. This is very common – first check whether you are using 32-bit or 64-bit Windows, then install the application for your version. This problem can also occur when you try to run an older 8-bit or 16-bit application on your modern 64-bit operating system. It may have run on a 32-bit operating system, but on a 64-bit Windows operating system because it can only emulate 32 bits.
2] Sometimes the download can be corrupted, so clear your browser’s cache and download and reinstall and check.
3] Log in with your Administrator account if possible and check if you can run it now. Right-click the application’s exe file and select Run as administrator. Does it work?
4] If the program shortcut causes this problem, open the program folder and see if you can run the main program from there.
5] Turn off your SmartScreen as a temporary workaround and see if it helps. Be sure to reactivate SmartScreen as it is a good security feature.
6] If you did not download the application from the Windows store but from another source, you may need to download the application from SideLoad assuming you trust App Publisher. You should only use SideLoad apps if you trust them completely.
7] Make a clean start and see if you can run it. If possible, you should manually identify and eliminate the offensive process that prevents Windows from running the application in the normal boot process. Remember to leave the Clean Boot State state once you have completed troubleshooting.
I hope something will help you solve the problem.
See this message if you have blocked an application for your protection message.
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